Background: Cancer patients  pts  are more than tice as likely to enter bankruptcy as the general US population. It is unknon ho often pts ith metastatic cancer are concerned about the financial toxicities  FTox  of treatment. Methods: As part of the larger  ;Living ith Cancer ; project e prospectively surveyed 941 pts ith advanced malignancies receiving treatment ith non-curative intent at 6 Ne Jersey cancer programs ithin the Regional Cancer Care Associates netork. Pts ere asked 2 questions about the financial burden and pain associated ith cancer  5-point Likert scale . Results: Pts felt that  ;Living ith Cancer has impacted the financial ell-being of me or my family ; severely 44 pts  5 percent , significantly 124 pts  14 percent  moderately 193 pts  21 percent , minimally 250 pts  28 percent  or not at all 292 pts  32 percent . For comparison, pts felt  ;Living ith Cancer the pain I experience is ; unbearableconstant 12 pts  1 percent , severe 82 pts  9 percent , moderate 209 pts  23 percent , mild 306 pts  34 percent , non-existent 294 pts  33 percent . Responses ere flagged as concerned if rated severe, significant or moderate. Concern about FTox as more prevalent than about pain  p lt 0.005 . FTox and pain responses had a eak positive correlation  r = 0.370; p lt 0.001 . Utilizing median household income per zip code as a surrogate  n = 867 , logistic regression demonstrated that as income increases the probability of being concerned about FTox decreases significantly  p lt 0.001 . A pt ith median US income of  51,000 has a 48 percent chance of being concerned about FTox, hereas a pt ith income of  151,000 has a 23 percent chance. Younger pts also ere significantly  p lt 0.001  more concerned about FTox; 30 yr 82 percent, 60 yr 48 percent and 80 yr 24 percent. Pts ith liquid malignancies had a higher proportion of concerned pts than solid malignancies  liquid 104218 concerned, solid 241644 concerned, p lt 0.005 . Conclusions: Financial toxicity concerns are common among pts ith metastaticadvanced cancers, being self-reported in 40 percent of pts of this NJ series. FTox concerns ere more prevalent than concern about pain, and ere more common in pts ith liquid rather than solid malignancies. Younger pts and those ho live in less affluent neighborhoods are more likely to be concerned about the FTox of cancer care.,J Clin Oncol 34, 2016  suppl; abstr 10065 00:00.0,Patient and Survivor Care