PubMed:25962635 / 701-1546 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T190	0-6	SO:0001026	denotes	Genome
T191	58-62	PR:Q8MQJ9	denotes	BRAT
T192	71-74	PR:000001890	denotes	PUM
T193	71-74	PR:000013492	denotes	PUM
T194	71-74	PR:P25822	denotes	PUM
T195	71-74	PR:P15941	denotes	PUM
T196	71-74	P15941	denotes	PUM
T197	78-88	2294143	denotes	Drosophila
T198	78-88	504603	denotes	Drosophila
T199	78-88	2294139	denotes	Drosophila
T200	78-88	2294145	denotes	Drosophila
T201	78-88	2294141	denotes	Drosophila
T202	78-88	2294142	denotes	Drosophila
T203	78-88	2294144	denotes	Drosophila
T204	78-88	2294140	denotes	Drosophila
T205	78-88	D004330	denotes	Drosophila
T206	78-88	2080301	denotes	Drosophila
T207	130-141	SO:0000068	denotes	overlapping
T208	157-161	PR:Q8MQJ9	denotes	BRAT
T209	186-194	CHEBI:36080	denotes	proteins
T210	288-291	PR:000001890	denotes	PUM
T211	288-291	PR:000013492	denotes	PUM
T212	288-291	PR:P25822	denotes	PUM
T213	288-291	PR:P15941	denotes	PUM
T214	288-291	P15941	denotes	PUM
T215	387-390	CHEBI:33697	denotes	RNA
T216	387-390	D012313	denotes	RNA
T217	387-390	GO:0005562	denotes	RNA
T219	387-396	SO:0000715	denotes	RNA motif
T222	411-415	PR:Q8MQJ9	denotes	BRAT
T223	429-433	PR:Q8MQJ9	denotes	BRAT
T224	443-453	GO:0065007	denotes	regulation
T225	457-463	UBERON:0000479	denotes	tissue
T226	504-508	PR:Q8MQJ9	denotes	BRAT
T227	556-560	PR:Q8MQJ9	denotes	BRAT
T228	585-595	GO:0065007	denotes	regulation
T229	620-632	32644	denotes	unidentified
T230	641-651	SO:0000673	denotes	transcript
T231	652-663	GO:0009056	denotes	degradation
T232	719-723	PR:Q8MQJ9	denotes	BRAT
T233	834-844	SO:1000009	denotes	transition

Id	Subject	Object	Predicate	Lexical cue
T2	0-845	RESULTS	denotes	Genome-wide identification of transcripts associated with BRAT or with PUM in Drosophila embryos shows that they bind largely non-overlapping sets of mRNAs. BRAT binds mRNAs that encode proteins associated with a variety of functions, many of which are distinct from those implemented by PUM-associated transcripts. Computational analysis of in vitro and in vivo data identified a novel RNA motif recognized by BRAT that confers BRAT-mediated regulation in tissue culture cells. The regulatory status of BRAT-associated mRNAs suggests a prominent role for BRAT in post-transcriptional regulation, including a previously unidentified role in transcript degradation. Transcriptomic analysis of embryos lacking functional BRAT reveals an important role in mediating the decay of hundreds of maternal mRNAs during the maternal-to-zygotic transition.

Id	Subject	Object	Predicate	Lexical cue
T5	142-146	CVCL_WY71\|Spontaneously_immortalized_cell_line\|Oncorhynchus keta	denotes	sets
T6	211-212	CVCL_6479\|Finite_cell_line\|Mus musculus	denotes	a
T7	379-380	CVCL_6479\|Finite_cell_line\|Mus musculus	denotes	a
T8	535-536	CVCL_6479\|Finite_cell_line\|Mus musculus	denotes	a
T9	607-608	CVCL_6479\|Finite_cell_line\|Mus musculus	denotes	a
T10	732-734	CVCL_8754\|Cancer_cell_line\|Homo sapiens	denotes	an
T11	732-734	CVCL_H241\|Cancer_cell_line\|Homo sapiens	denotes	an