PubMed:25404436 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/25404436","sourcedb":"PubMed","sourceid":"25404436","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/25404436","text":"Efficacy of clarithromycin in pityriasis rosea.\nOBJECTIVE: To determine the efficacy of clarithromycin in the treatment of Pityriasis Rosea (PR).\nSTUDY DESIGN: Double blind randomized controlled trial.\nPLACE AND DURATION OF STUDY: Dermatology OPD, Military Hospital, Rawalpindi, from July 2008 to July 2009.\nMETHODOLOGY: Patients aged above 10 years, diagnosed with PR, were randomly assigned to two groups of 30 each to receive either clarithromycin or similar-looking placebo for one week. Neither the patient nor the treating physician knew to which group the patient belonged. Patients were assessed at 1, 2, 4 and 6 weeks after presentation and compared for complete, partial or no response.\nRESULTS: Among the 60 patients, no significant difference was found between the two groups at 2 weeks after presentation (p = 0.598). In the placebo group, complete response was seen in 20 (66.7%), partial response in 3 (10.0%) while no response was seen in 7 (23.3%). In clarithromycin group, there was complete response in 23 (76.7%), partial response in 3 (10.0%) and no response in 4 (13.3%) patients.\nCONCLUSION: Clarithromycin is not effective in treatment of pityriasis rosea.","tracks":[]}