PubMed:23590276
Annnotations
PubMed_ArguminSci
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 78-181 | DRI_Challenge | denotes | This study outlines the potential of a novel therapeutic dressing for the management of chronic wounds. |
T2 | 182-332 | DRI_Background | denotes | The dressing incorporates polyphosphate, a non toxic compound with a number of beneficial characteristics in terms of wound healing, in a foam matrix. |
T3 | 333-548 | DRI_Background | denotes | The aim of this study was to identify the potential of polyphosphate incorporated in the foam dressing to sequester the activity of matrix metalloproteinases (MMPs) and proteases derived from Pseudomonas aeruginosa. |
T4 | 549-626 | DRI_Background | denotes | Methods used included gelatin zymography and milk-casein agar plate analysis. |
T5 | 627-792 | DRI_Outcome | denotes | Results have shown that this dressing is effectively capable of reducing the levels of MMP-2 and MMP-9 in both their active and latent forms using an in vitro model. |
T6 | 793-902 | DRI_Outcome | denotes | The dressing also demonstrated the compound's potential in the regulation of P. aeruginosa derived proteases. |
Goldhamster2_Cellosaurus
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 115-116 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
T2 | 223-224 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
T3 | 249-250 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
T4 | 318-319 | CVCL_6479|Finite_cell_line|Mus musculus | denotes | a |
T5 | 453-461 | CVCL_C410|Hybridoma|Mus musculus | denotes | activity |
T6 | 611-616 | CVCL_B488|Transformed_cell_line|Homo sapiens | denotes | plate |
T7 | 744-750 | CVCL_C410|Hybridoma|Mus musculus | denotes | active |
T8 | 774-776 | CVCL_8754|Cancer_cell_line|Homo sapiens | denotes | an |
T9 | 774-776 | CVCL_H241|Cancer_cell_line|Homo sapiens | denotes | an |
GoldHamster
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 12-26 | D011122 | denotes | polyphosphates |
T2 | 12-26 | CHEBI:26197 | denotes | polyphosphates |
T3 | 12-26 | D011122 | denotes | polyphosphates |
T4 | 51-57 | UBERON:0027368 | denotes | matrix |
T5 | 51-76 | D020782 | denotes | matrix metalloproteinases |
T7 | 208-221 | CHEBI:16838 | denotes | polyphosphate |
T8 | 300-313 | GO:0042060 | denotes | wound healing |
T9 | 325-331 | UBERON:0027368 | denotes | matrix |
T10 | 388-401 | CHEBI:16838 | denotes | polyphosphate |
T11 | 465-471 | UBERON:0027368 | denotes | matrix |
T12 | 465-490 | D020782 | denotes | matrix metalloproteinases |
T14 | 492-496 | D020782 | denotes | MMPs |
T15 | 502-511 | D010447 | denotes | proteases |
T17 | 525-547 | 287 | denotes | Pseudomonas aeruginosa |
T18 | 525-547 | D011550 | denotes | Pseudomonas aeruginosa |
T19 | 571-578 | 4716 | denotes | gelatin |
T20 | 571-578 | D005780 | denotes | gelatin |
T21 | 571-578 | CHEBI:5291 | denotes | gelatin |
T22 | 594-598 | UBERON:0001913 | denotes | milk |
T24 | 599-605 | 862460 | denotes | casein |
T23 | 599-605 | CHEBI:3448 | denotes | casein |
T25 | 599-605 | D002364 | denotes | casein |
T29 | 606-610 | 397 | denotes | agar |
T28 | 606-610 | PR:000032943 | denotes | agar |
T31 | 606-610 | PR:P0ACK2 | denotes | agar |
T26 | 606-610 | D000362 | denotes | agar |
T27 | 606-610 | D000362 | denotes | agar |
T30 | 606-610 | CHEBI:2509 | denotes | agar |
T32 | 611-616 | UBERON:6004475 | denotes | plate |
T33 | 611-616 | UBERON:0003148 | denotes | plate |
T34 | 714-717 | CHEBI:340824 | denotes | MMP |
T37 | 714-717 | CHEBI:59761 | denotes | MMP |
T38 | 714-719 | PR:P08253 | denotes | MMP-2 |
T39 | 714-719 | Q9GLE5 | denotes | MMP-2 |
T40 | 714-719 | P08253 | denotes | MMP-2 |
T41 | 714-719 | Q90611 | denotes | MMP-2 |
T43 | 714-719 | PR:Q8MPP3 | denotes | MMP-2 |
T44 | 714-719 | P33436 | denotes | MMP-2 |
T45 | 714-719 | PR:Q90611 | denotes | MMP-2 |
T46 | 714-719 | PR:P33436 | denotes | MMP-2 |
T47 | 714-719 | PR:000010479 | denotes | MMP-2 |
T48 | 714-719 | PR:P33434 | denotes | MMP-2 |
T49 | 714-719 | P33434 | denotes | MMP-2 |
T50 | 714-719 | P50757 | denotes | MMP-2 |
T42 | 714-719 | GO:0004228 | denotes | MMP-2 |
T51 | 724-727 | CHEBI:340824 | denotes | MMP |
T54 | 724-727 | CHEBI:59761 | denotes | MMP |
T55 | 724-729 | PR:P50282 | denotes | MMP-9 |
T56 | 724-729 | PR:P14780 | denotes | MMP-9 |
T57 | 724-729 | P14780 | denotes | MMP-9 |
T58 | 724-729 | PR:P41245 | denotes | MMP-9 |
T59 | 724-729 | P41246 | denotes | MMP-9 |
T60 | 724-729 | P41245 | denotes | MMP-9 |
T61 | 724-729 | PR:P52176 | denotes | MMP-9 |
T62 | 724-729 | P50282 | denotes | MMP-9 |
T64 | 724-729 | PR:000010491 | denotes | MMP-9 |
T65 | 724-729 | P52176 | denotes | MMP-9 |
T66 | 724-729 | O18733 | denotes | MMP-9 |
T63 | 724-729 | GO:0004229 | denotes | MMP-9 |
T67 | 856-866 | GO:0065007 | denotes | regulation |
T68 | 892-901 | D010447 | denotes | proteases |