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PubMed_Structured_Abstracts

Id Subject Object Predicate Lexical cue
T1 108-365 BACKGROUND denotes Our previous study suggested that porcine pancreatic extract in hamsters with peripheral insulin resistance, normalizes insulin output, islet size and pancreatic DNA synthetic rate. It also inhibited the growth of human pancreatic cancer cells in nude mice.
T2 377-535 OBJECTIVE denotes To examine the potential value of the porcine pancreatic extract in controlling pancreatic carcinogenesis in this model, the present experiment was performed.
T3 544-1270 METHODS denotes Hamsters were fed a high fat diet and four weeks later when insulin resistance emerges, they were divided into two groups. One group received 1 g/kg BW of porcine pancreatic extract in drinking water and the other group received tap water. One week later, when insulin output normalizes in porcine pancreatic extract-treated hamsters, a single subcutaneous injection of N-nitrosobis-(2-oxopropyl) amine (BOP) at a dose of 40 mg/kg BW was given to all hamsters. The experiment was terminated at 43 weeks after the porcine pancreatic extract treatment. The number and size of pancreatic tumors, blood glucose, insulin, amylase and lipase levels, the average size of islets and the number of insulin cells/islets were determined.
T4 1280-1638 RESULTS denotes The incidence of pancreatic cancer was significantly lower in the porcine pancreatic extract group (P=0.043), as well as the plasma insulin level and the size of the islets in the porcine pancreatic extract group were significantly lower (P<0.001) than in the control group. No significantly differences were found in the glucose level between the groups.
T5 1651-1754 CONCLUSIONS denotes These results show that porcine pancreatic extract has a potential to inhibit pancreatic cancer growth.

Goldhamster2_Cellosaurus

Id Subject Object Predicate Lexical cue
T1 339-345 CVCL_E025|Induced_pluripotent_stem_cell|Homo sapiens denotes cancer
T2 562-563 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T3 667-670 CVCL_Z424|Spontaneously_immortalized_cell_line|Ostrinia nubilalis denotes One
T4 784-787 CVCL_Z424|Spontaneously_immortalized_cell_line|Ostrinia nubilalis denotes One
T5 879-880 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T6 956-957 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T7 966-968 CVCL_IW90|Cancer_cell_line|Mus musculus denotes 40
T8 1038-1040 CVCL_UU94|Spontaneously_immortalized_cell_line|Cricetulus griseus denotes 43
T9 1308-1314 CVCL_E025|Induced_pluripotent_stem_cell|Homo sapiens denotes cancer
T10 1521-1523 CVCL_8891|Finite_cell_line|Homo sapiens denotes lt
T11 1702-1705 CVCL_6758|Undefined_cell_line_type|Cricetulus griseus denotes has
T12 1702-1705 CVCL_E689|Transformed_cell_line|Homo sapiens denotes has
T13 1706-1707 CVCL_6479|Finite_cell_line|Mus musculus denotes a
T14 1740-1746 CVCL_E025|Induced_pluripotent_stem_cell|Homo sapiens denotes cancer

GoldHamster

Id Subject Object Predicate Lexical cue
T1 45-53 UBERON:3011040 denotes pancreas
T2 45-53 UBERON:0001264 denotes pancreas
T3 57-65 D006224 denotes hamsters
T4 75-89 D063646 denotes carcinogenesis
T5 75-89 D063646 denotes carcinogenesis
T6 150-168 D010184 denotes pancreatic extract
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T184 270-273 GO:0005574 denotes DNA
T186 270-273 SO:0000352 denotes DNA
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T187 270-273 D004247 denotes DNA
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T189 322-327 D006801 denotes human
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T191 328-345 D010190 denotes pancreatic cancer
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T202 355-364 10090 denotes nude mice
T203 355-364 D008819 denotes nude mice
T204 360-364 PR:000005054 denotes mice
T206 360-364 O89094 denotes mice
T208 423-441 D010184 denotes pancreatic extract
T209 468-482 D063646 denotes carcinogenesis
T210 468-482 D063646 denotes carcinogenesis
T211 544-552 D006224 denotes Hamsters
T212 569-572 UBERON:0001013 denotes fat
T213 569-572 CHEBI:24021 denotes fat
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T302 604-622 D007333 denotes insulin resistance
T303 707-725 D010184 denotes pancreatic extract
T304 729-743 D060766 denotes drinking water
T305 729-743 D060766 denotes drinking water
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T422 914-946 C013622 denotes N-nitrosobis-(2-oxopropyl) amine
T423 914-946 C013622 denotes N-nitrosobis-(2-oxopropyl) amine
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T443 1129-1135 D009369 denotes tumors
T444 1129-1135 D009369 denotes tumors
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T558 1233-1240 P01308 denotes insulin
T559 1233-1240 P01340 denotes insulin
T560 1233-1240 P07453 denotes insulin
T561 1233-1240 P68988 denotes insulin
T562 1233-1240 P21563 denotes insulin
T563 1233-1240 P68245 denotes insulin
T564 1233-1240 P68990 denotes insulin
T566 1233-1240 P09476 denotes insulin
T567 1233-1240 P69047 denotes insulin
T568 1233-1240 Q8HXV2 denotes insulin
T569 1233-1240 P12705 denotes insulin
T570 1233-1240 P68987 denotes insulin
T572 1233-1240 Q9NDE7 denotes insulin
T573 1233-1240 P13190 denotes insulin
T574 1233-1240 P01321 denotes insulin
T575 1233-1240 C0HJT9 denotes insulin
T576 1233-1240 P81423 denotes insulin
T577 1233-1240 P01327 denotes insulin
T578 1233-1240 P41522 denotes insulin
T579 1233-1240 C0HJI1 denotes insulin
T580 1233-1240 P01336 denotes insulin
T581 1233-1240 P67974 denotes insulin
T582 1233-1240 P69046 denotes insulin
T583 1233-1240 P12704 denotes insulin
T584 1233-1240 P42633 denotes insulin
T585 1233-1240 P67968 denotes insulin
T586 1233-1240 P01334 denotes insulin
T587 1233-1240 P67973 denotes insulin
T588 1233-1240 P01328 denotes insulin
T589 1233-1240 P81881 denotes insulin
T590 1233-1240 P01330 denotes insulin
T591 1233-1240 Q9W7R2 denotes insulin
T592 1233-1240 P09477 denotes insulin
T593 1233-1240 P01311 denotes insulin
T594 1233-1240 P01315 denotes insulin
T595 1233-1240 P06306 denotes insulin
T596 1233-1240 P01319 denotes insulin
T597 1233-1240 Q6YK33 denotes insulin
T598 1233-1240 P67971 denotes insulin
T599 1233-1240 Q62587 denotes insulin
T600 1233-1240 P68991 denotes insulin
T601 1233-1240 P12708 denotes insulin
T602 1233-1240 P04667 denotes insulin
T604 1233-1240 P68989 denotes insulin
T605 1233-1240 P01333 denotes insulin
T606 1233-1240 PR:000009054 denotes insulin
T607 1233-1240 P30410 denotes insulin
T608 1233-1240 P01331 denotes insulin
T609 1233-1240 P01314 denotes insulin
T610 1233-1240 P01320 denotes insulin
T611 1233-1240 P01318 denotes insulin
T612 1233-1240 P12703 denotes insulin
T613 1233-1240 C0HJI4 denotes insulin
T614 1233-1240 P30406 denotes insulin
T615 1233-1240 C0HJU0 denotes insulin
T616 1233-1240 P68992 denotes insulin
T617 1233-1240 P67970 denotes insulin
T618 1233-1240 P18109 denotes insulin
T619 1233-1240 Q9TQY7 denotes insulin
T620 1233-1240 O73727 denotes insulin
T621 1233-1240 P01329 denotes insulin
T622 1233-1240 P01324 denotes insulin
T624 1233-1240 P01335 denotes insulin
T625 1233-1240 P68243 denotes insulin
T626 1233-1240 P67972 denotes insulin
T627 1233-1240 P29335 denotes insulin
T628 1233-1240 P01342 denotes insulin
T629 1233-1240 P69048 denotes insulin
T630 1233-1240 P01313 denotes insulin
T631 1233-1240 P01316 denotes insulin
T632 1233-1240 P17715 denotes insulin
T633 1233-1240 P30407 denotes insulin
T634 1233-1240 P01339 denotes insulin
T636 1233-1240 P81025 denotes insulin
T637 1233-1240 P69045 denotes insulin
T638 1233-1240 P01317 denotes insulin
T639 1233-1240 P01310 denotes insulin
T640 1233-1240 Q98TA8 denotes insulin
T641 1233-1240 P67969 denotes insulin
T642 1233-1240 P0C236 denotes insulin
T565 1233-1240 CHEBI:5931 denotes insulin
T571 1233-1240 D007328 denotes insulin
T603 1233-1240 CHEBI:145810 denotes insulin
T623 1233-1240 D007328 denotes insulin
T635 1233-1240 GO:0016088 denotes insulin
T643 1297-1314 D010190 denotes pancreatic cancer
T644 1297-1314 D010190 denotes pancreatic cancer
T645 1354-1372 D010184 denotes pancreatic extract
T646 1405-1411 UBERON:0001969 denotes plasma
T647 1412-1419 P51463 denotes insulin
T648 1412-1419 Q91XI3 denotes insulin
T649 1412-1419 P01308 denotes insulin
T650 1412-1419 P01340 denotes insulin
T651 1412-1419 P07453 denotes insulin
T652 1412-1419 P68988 denotes insulin
T653 1412-1419 P21563 denotes insulin
T654 1412-1419 P68245 denotes insulin
T655 1412-1419 P68990 denotes insulin
T657 1412-1419 P09476 denotes insulin
T658 1412-1419 P69047 denotes insulin
T659 1412-1419 Q8HXV2 denotes insulin
T660 1412-1419 P12705 denotes insulin
T661 1412-1419 P68987 denotes insulin
T663 1412-1419 Q9NDE7 denotes insulin
T664 1412-1419 P13190 denotes insulin
T665 1412-1419 P01321 denotes insulin
T666 1412-1419 C0HJT9 denotes insulin
T667 1412-1419 P81423 denotes insulin
T668 1412-1419 P01327 denotes insulin
T669 1412-1419 P41522 denotes insulin
T670 1412-1419 C0HJI1 denotes insulin
T671 1412-1419 P01336 denotes insulin
T672 1412-1419 P67974 denotes insulin
T673 1412-1419 P69046 denotes insulin
T674 1412-1419 P12704 denotes insulin
T675 1412-1419 P42633 denotes insulin
T676 1412-1419 P67968 denotes insulin
T677 1412-1419 P01334 denotes insulin
T678 1412-1419 P67973 denotes insulin
T679 1412-1419 P01328 denotes insulin
T680 1412-1419 P81881 denotes insulin
T681 1412-1419 P01330 denotes insulin
T682 1412-1419 Q9W7R2 denotes insulin
T683 1412-1419 P09477 denotes insulin
T684 1412-1419 P01311 denotes insulin
T685 1412-1419 P01315 denotes insulin
T686 1412-1419 P06306 denotes insulin
T687 1412-1419 P01319 denotes insulin
T688 1412-1419 Q6YK33 denotes insulin
T689 1412-1419 P67971 denotes insulin
T690 1412-1419 Q62587 denotes insulin
T691 1412-1419 P68991 denotes insulin
T692 1412-1419 P12708 denotes insulin
T693 1412-1419 P04667 denotes insulin
T695 1412-1419 P68989 denotes insulin
T696 1412-1419 P01333 denotes insulin
T697 1412-1419 PR:000009054 denotes insulin
T698 1412-1419 P30410 denotes insulin
T699 1412-1419 P01331 denotes insulin
T700 1412-1419 P01314 denotes insulin
T701 1412-1419 P01320 denotes insulin
T702 1412-1419 P01318 denotes insulin
T703 1412-1419 P12703 denotes insulin
T704 1412-1419 C0HJI4 denotes insulin
T705 1412-1419 P30406 denotes insulin
T706 1412-1419 C0HJU0 denotes insulin
T707 1412-1419 P68992 denotes insulin
T708 1412-1419 P67970 denotes insulin
T709 1412-1419 P18109 denotes insulin
T710 1412-1419 Q9TQY7 denotes insulin
T711 1412-1419 O73727 denotes insulin
T712 1412-1419 P01329 denotes insulin
T713 1412-1419 P01324 denotes insulin
T715 1412-1419 P01335 denotes insulin
T716 1412-1419 P68243 denotes insulin
T717 1412-1419 P67972 denotes insulin
T718 1412-1419 P29335 denotes insulin
T719 1412-1419 P01342 denotes insulin
T720 1412-1419 P69048 denotes insulin
T721 1412-1419 P01313 denotes insulin
T722 1412-1419 P01316 denotes insulin
T723 1412-1419 P17715 denotes insulin
T724 1412-1419 P30407 denotes insulin
T725 1412-1419 P01339 denotes insulin
T727 1412-1419 P81025 denotes insulin
T728 1412-1419 P69045 denotes insulin
T729 1412-1419 P01317 denotes insulin
T730 1412-1419 P01310 denotes insulin
T731 1412-1419 Q98TA8 denotes insulin
T732 1412-1419 P67969 denotes insulin
T733 1412-1419 P0C236 denotes insulin
T656 1412-1419 CHEBI:5931 denotes insulin
T662 1412-1419 D007328 denotes insulin
T694 1412-1419 CHEBI:145810 denotes insulin
T714 1412-1419 D007328 denotes insulin
T726 1412-1419 GO:0016088 denotes insulin
T734 1468-1486 D010184 denotes pancreatic extract
T737 1605-1612 4850 denotes glucose
T735 1605-1612 D005947 denotes glucose
T736 1605-1612 D005947 denotes glucose
T738 1605-1612 CHEBI:42758 denotes glucose
T739 1605-1612 CHEBI:4167 denotes glucose
T740 1605-1612 CHEBI:17234 denotes glucose
T741 1683-1701 D010184 denotes pancreatic extract
T742 1729-1746 D010190 denotes pancreatic cancer
T743 1729-1746 D010190 denotes pancreatic cancer

PubmedHPO

Id Subject Object Predicate Lexical cue
T1 197-215 HP_0000855 denotes insulin resistance
T2 328-345 HP_0002894 denotes pancreatic cancer
T3 339-345 HP_0002664 denotes cancer