PubMed:1969745 JSONTXT

{"project":"Inflammaging","denotations":[{"id":"T1","span":{"begin":0,"end":152},"obj":"Sentence"},{"id":"T2","span":{"begin":153,"end":404},"obj":"Sentence"},{"id":"T3","span":{"begin":405,"end":597},"obj":"Sentence"},{"id":"T4","span":{"begin":598,"end":789},"obj":"Sentence"},{"id":"T1","span":{"begin":0,"end":152},"obj":"Sentence"},{"id":"T2","span":{"begin":153,"end":404},"obj":"Sentence"},{"id":"T3","span":{"begin":405,"end":597},"obj":"Sentence"},{"id":"T4","span":{"begin":598,"end":789},"obj":"Sentence"}],"text":"T-cell inducer populations in cutaneous inflammation: a predominance of T helper-inducer lymphocytes (THi) in the infiltrate of inflammatory dermatoses.\nThe mononuclear infiltrate found in a variety of inflammatory dermatoses was characterized by a predominance of T helper-inducer lymphocytes (THi), CD4+/CD45RA-/CD45RO+, a population of cells responsible for maintaining and promoting immune reactions. Only small numbers of T-suppressor-inducer lymphocytes (TSi), CD4+/CD45RA+/CD45RO-, cells responsible for inducing CD8 suppressor-effector cells to 'down regulate' immune reactions, were seen. The predominance of CD4+ THi lymphocytes was common to all dermatoses studied and suggests a common final pathway in chronic cutaneous inflammation, irrespective of initial causative factors."}