Glycosylation of acid sensitive acceptors. Synthesis of (2,3-epoxy-1-propyl) glycosides.
Treatment of O-benzylated derivatives of glycosyl N-allyl thiocarbamate with racemic or enantiomerically pure glycidol and bromine provides the 1,2-cis-glycidyl glycosides. This protocol was mild, highly stereoselective and efficient.