PubMed:10224109
Annnotations
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-182 | Sentence | denotes | Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation. |
| T2 | 183-290 | Sentence | denotes | PG490 (triptolide) is a diterpene triepoxide with potent immunosuppressive and antiinflammatory properties. |
| T3 | 291-526 | Sentence | denotes | PG490 inhibits interleukin(IL)-2 expression by normal human peripheral blood lymphocytes stimulated with phorbol 12-myristate 13-acetate (PMA) and antibody to CD3 (IC50 of 10 ng/ml), and with PMA and ionomycin (Iono, IC50 of 40 ng/ml). |
| T4 | 527-600 | Sentence | denotes | In Jurkat T-cells, PG490 inhibits PMA/Iono-stimulated IL-2 transcription. |
| T5 | 601-803 | Sentence | denotes | PG490 inhibits the induction of DNA binding activity at the purine-box/antigen receptor response element (ARRE)/nuclear factor of activated T-cells (NF-AT) target sequence but not at the NF-kappaB site. |
| T6 | 804-1003 | Sentence | denotes | PG490 can completely inhibit transcriptional activation at the purine-box/ARRE/NF-AT and NF-kappaB target DNA sequences triggered by all stimuli examined (PMA, PMA/Iono, tumor necrosis factor-alpha). |
| T7 | 1004-1196 | Sentence | denotes | PG490 also inhibits PMA-stimulated activation of a chimeric transcription factor in which the C-terminal TA1 transactivation domain of NF-kappaB p65 is fused to the DNA binding domain of GAL4. |
| T8 | 1197-1371 | Sentence | denotes | In 16HBE human bronchial epithelial cells, IL-8 expression is regulated predominantly by NF-kappaB, and PG490 but not cyclosporin A can completely inhibit expression of IL-8. |
| T9 | 1372-1635 | Sentence | denotes | The mechanism of PG490 inhibition of cytokine gene expression differs from cyclosporin A and involves nuclear inhibition of transcriptional activation of NF-kappaB and the purine-box regulator operating at the ARRE/NF-AT site at a step after specific DNA binding. |
Glycosmos6-MAT
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 362-367 | http://purl.obolibrary.org/obo/MAT_0000083 | denotes | blood |
| T2 | 362-367 | http://purl.obolibrary.org/obo/MAT_0000315 | denotes | blood |
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 46-66 | protein | denotes | T-cell interleukin-2 |
| T2 | 94-119 | protein | denotes | purine-box/nuclear factor |
| T3 | 123-140 | cell_type | denotes | activated T-cells |
| T4 | 145-154 | protein | denotes | NF-kappaB |
| T5 | 306-323 | protein | denotes | interleukin(IL)-2 |
| T6 | 338-379 | cell_type | denotes | normal human peripheral blood lymphocytes |
| T7 | 450-453 | protein | denotes | CD3 |
| T8 | 530-544 | cell_line | denotes | Jurkat T-cells |
| T9 | 581-585 | protein | denotes | IL-2 |
| T10 | 661-772 | DNA | denotes | purine-box/antigen receptor response element (ARRE)/nuclear factor of activated T-cells (NF-AT) target sequence |
| T11 | 788-802 | DNA | denotes | NF-kappaB site |
| T12 | 867-923 | DNA | denotes | purine-box/ARRE/NF-AT and NF-kappaB target DNA sequences |
| T13 | 974-1001 | protein | denotes | tumor necrosis factor-alpha |
| T14 | 1055-1084 | protein | denotes | chimeric transcription factor |
| T15 | 1098-1135 | protein | denotes | C-terminal TA1 transactivation domain |
| T16 | 1139-1152 | protein | denotes | NF-kappaB p65 |
| T17 | 1169-1187 | protein | denotes | DNA binding domain |
| T18 | 1191-1195 | protein | denotes | GAL4 |
| T19 | 1200-1238 | cell_type | denotes | 16HBE human bronchial epithelial cells |
| T20 | 1240-1244 | protein | denotes | IL-8 |
| T21 | 1286-1295 | protein | denotes | NF-kappaB |
| T22 | 1366-1370 | protein | denotes | IL-8 |
| T23 | 1409-1422 | DNA | denotes | cytokine gene |
| T24 | 1526-1535 | protein | denotes | NF-kappaB |
| T25 | 1544-1564 | DNA | denotes | purine-box regulator |
| T26 | 1582-1597 | DNA | denotes | ARRE/NF-AT site |
semrep-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| E1-ti-1 | 0-17 | cui:C0021081 | denotes | Immunosuppressant |
| E2-ti-1 | 18-23 | cui:C0971326 | denotes | PG490 |
| E3-ti-1 | 25-35 | cui:C0077274 | denotes | triptolide |
| E4-ti-1 | 46-52 | cui:C0039194 | denotes | T-cell |
| E5-ti-1 | 53-66 | cui:C0021756 | denotes | interleukin-2 |
| E6-ti-1 | 67-77 | cui:C0185117 | denotes | expression |
| E7-ti-1 | 94-100 | cui:C0034140 | denotes | purine |
| E8-ti-1 | 101-104 | cui:C0179400 | denotes | box |
| E9-ti-1 | 105-112 | cui:C0521447 | denotes | nuclear |
| E10-ti-1 | 113-119 | cui:C1521761 | denotes | factor |
| E11-ti-1 | 123-132 | cui:C1515877 | denotes | activated |
| E12-ti-1 | 133-140 | cui:C0039194 | denotes | T-cells |
| E13-ti-1 | 145-154 | cui:C0079904 | denotes | NF-kappaB |
| E14-ti-1 | 155-181 | cui:C0162493 | denotes | transcriptional activation |
| T1 | 0-23 | ISA | denotes | Immunosuppressant PG490 |
| T2 | 18-35 | ISA | denotes | PG490 (triptolide |
| T3 | 37-45 | INHIBITS | denotes | inhibits |
| T4 | 46-66 | PART_OF | denotes | T-cell interleukin-2 |
| E1-ab-1 | 183-188 | cui:C0971326 | denotes | PG490 |
| E2-ab-1 | 190-200 | cui:C0077274 | denotes | triptolide |
| E3-ab-1 | 207-216 | cui:C0012780 | denotes | diterpene |
| E4-ab-1 | 233-239 | cui:C0237399 | denotes | potent |
| E5-ab-1 | 279-289 | cui:C0871161 | denotes | properties |
| T5 | 183-200 | ISA | denotes | PG490 (triptolide |
| E1-ab-2 | 291-296 | cui:C0971326 | denotes | PG490 |
| E2-ab-2 | 306-317 | cui:C0021764 | denotes | interleukin |
| E3-ab-2 | 318-323 | cui:C0879590 | denotes | IL)-2 |
| E4-ab-2 | 324-334 | cui:C0185117 | denotes | expression |
| E5-ab-2 | 338-344 | cui:C0205307 | denotes | normal |
| E6-ab-2 | 345-350 | cui:C0020114 | denotes | human |
| E7-ab-2 | 351-379 | cui:C1518997 | denotes | peripheral blood lymphocytes |
| E8-ab-2 | 396-427 | cui:C0039654 | denotes | phorbol 12-myristate 13-acetate |
| E9-ab-2 | 438-446 | cui:C0003241 | denotes | antibody |
| E10-ab-2 | 455-459 | cui:C0600495 | denotes | IC50 |
| E11-ab-2 | 483-486 | cui:C0039654 | denotes | PMA |
| E12-ab-2 | 491-500 | cui:C0022020 | denotes | ionomycin |
| E13-ab-2 | 508-512 | cui:C0600495 | denotes | IC50 |
| T6 | 297-305 | INHIBITS | denotes | inhibits |
| T7 | 345-379 | PART_OF | denotes | human peripheral blood lymphocytes |
| T8 | 380-390 | STIMULATES | denotes | stimulated |
| T9 | 380-390 | STIMULATES | denotes | stimulated |
| E1-ab-3 | 530-544 | cui:C0376448 | denotes | Jurkat T-cells |
| E2-ab-3 | 546-551 | cui:C0971326 | denotes | PG490 |
| E3-ab-3 | 561-564 | cui:C0039654 | denotes | PMA |
| E4-ab-3 | 581-585 | cui:C0879590 | denotes | IL-2 |
| E5-ab-3 | 586-599 | cui:C0040649 | denotes | transcription |
| T10 | 552-560 | INHIBITS | denotes | inhibits |
| E1-ab-4 | 601-606 | cui:C0971326 | denotes | PG490 |
| E2-ab-4 | 620-629 | cui:C0857127 | denotes | induction |
| E3-ab-4 | 633-644 | cui:C1148673 | denotes | DNA binding |
| E4-ab-4 | 645-653 | cui:C0439167 | denotes | activity |
| E5-ab-4 | 661-667 | cui:C0034140 | denotes | purine |
| E6-ab-4 | 668-671 | cui:C0179400 | denotes | box |
| E7-ab-4 | 672-688 | cui:C0034788 | denotes | antigen receptor |
| E8-ab-4 | 689-705 | cui:C0600508 | denotes | response element |
| E9-ab-4 | 713-748 | cui:C0288011 | denotes | nuclear factor of activated T-cells |
| E10-ab-4 | 764-772 | cui:C1519249 | denotes | sequence |
| E11-ab-4 | 777-780 | cui:C1518422 | denotes | not |
| E12-ab-4 | 788-797 | cui:C0079904 | denotes | NF-kappaB |
| E13-ab-4 | 798-802 | cui:C0205145 | denotes | site |
| E1-ab-5 | 804-809 | cui:C0971326 | denotes | PG490 |
| E2-ab-5 | 833-859 | cui:C0162493 | denotes | transcriptional activation |
| E3-ab-5 | 867-873 | cui:C0034140 | denotes | purine |
| E4-ab-5 | 874-877 | cui:C0179400 | denotes | box |
| E5-ab-5 | 878-882 | cui:C0034788 | denotes | ARRE |
| E6-ab-5 | 878-882 | cui:C0600508 | denotes | ARRE |
| E7-ab-5 | 883-888 | cui:C0288011 | denotes | NF-AT |
| E8-ab-5 | 893-902 | cui:C0079904 | denotes | NF-kappaB |
| E9-ab-5 | 910-923 | cui:C0162326 | denotes | DNA sequences |
| E10-ab-5 | 941-948 | cui:C0234402 | denotes | stimuli |
| E11-ab-5 | 959-962 | cui:C0039654 | denotes | PMA |
| E12-ab-5 | 964-967 | cui:C0039654 | denotes | PMA |
| E13-ab-5 | 974-1001 | cui:C1448177 | denotes | tumor necrosis factor-alpha |
| T11 | 825-832 | DISRUPTS | denotes | inhibit |
| E1-ab-6 | 1004-1009 | cui:C0971326 | denotes | PG490 |
| E2-ab-6 | 1024-1027 | cui:C0039654 | denotes | PMA |
| E3-ab-6 | 1055-1063 | cui:C0333678 | denotes | chimeric |
| E4-ab-6 | 1064-1084 | cui:C0040648 | denotes | transcription factor |
| E5-ab-6 | 1100-1108 | cui:C0205088 | denotes | terminal |
| E6-ab-6 | 1109-1112 | entrez:134864 | denotes | TA1 |
| E7-ab-6 | 1113-1128 | cui:C0040624 | denotes | transactivation |
| E8-ab-6 | 1139-1148 | cui:C0079904 | denotes | NF-kappaB |
| E9-ab-6 | 1149-1152 | cui:C0599933 | denotes | p65 |
| E10-ab-6 | 1169-1187 | cui:C1511662 | denotes | DNA binding domain |
| E11-ab-6 | 1191-1195 | entrez:3960 | denotes | GAL4 |
| T12 | 1039-1049 | STIMULATES | denotes | activation |
| E1-ab-7 | 1212-1221 | cui:C0205039 | denotes | bronchial |
| E2-ab-7 | 1222-1232 | cui:C0221908 | denotes | epithelial |
| E3-ab-7 | 1206-1238 | cui:C0427861 | denotes | human bronchial epithelial cells |
| E4-ab-7 | 1240-1244 | cui:C0079633 | denotes | IL-8 |
| E5-ab-7 | 1245-1255 | cui:C0185117 | denotes | expression |
| E6-ab-7 | 1286-1295 | cui:C0079904 | denotes | NF-kappaB |
| E7-ab-7 | 1301-1306 | cui:C0971326 | denotes | PG490 |
| E8-ab-7 | 1311-1314 | cui:C1518422 | denotes | not |
| E9-ab-7 | 1315-1328 | cui:C0010592 | denotes | cyclosporin A |
| E10-ab-7 | 1352-1362 | cui:C0185117 | denotes | expression |
| E11-ab-7 | 1366-1370 | cui:C0079633 | denotes | IL-8 |
| T13 | 1344-1351 | INHIBITS | denotes | inhibit |
| E1-ab-8 | 1376-1385 | cui:C0441712 | denotes | mechanism |
| E2-ab-8 | 1389-1394 | cui:C0971326 | denotes | PG490 |
| E3-ab-8 | 1409-1417 | cui:C0079189 | denotes | cytokine |
| E4-ab-8 | 1418-1433 | cui:C0017262 | denotes | gene expression |
| E5-ab-8 | 1447-1460 | cui:C0010592 | denotes | cyclosporin A |
| E6-ab-8 | 1474-1481 | cui:C0521447 | denotes | nuclear |
| E7-ab-8 | 1496-1522 | cui:C0162493 | denotes | transcriptional activation |
| E8-ab-8 | 1526-1535 | cui:C0079904 | denotes | NF-kappaB |
| E9-ab-8 | 1544-1550 | cui:C0034140 | denotes | purine |
| E10-ab-8 | 1551-1554 | cui:C0179400 | denotes | box |
| E11-ab-8 | 1582-1586 | cui:C0600508 | denotes | ARRE |
| E12-ab-8 | 1587-1592 | cui:C0288011 | denotes | NF-AT |
| E13-ab-8 | 1582-1597 | cui:C0034788 | denotes | ARRE/NF-AT site |
| E14-ab-8 | 1603-1607 | cui:C1261552 | denotes | step |
| E15-ab-8 | 1623-1634 | cui:C1148673 | denotes | DNA binding |
| T14 | 1395-1405 | INHIBITS | denotes | inhibition |
| T15 | 1482-1492 | DISRUPTS | denotes | inhibition |
| R1 | E2-ti-1 | T1 | subjectOf | PG490,Immunosuppressant PG490 |
| R2 | E1-ti-1 | T1 | objectOf | Immunosuppressant,Immunosuppressant PG490 |
| R3 | E2-ti-1 | T2 | subjectOf | PG490,PG490 (triptolide |
| R4 | E3-ti-1 | T2 | objectOf | triptolide,PG490 (triptolide |
| R5 | E2-ti-1 | T3 | subjectOf | PG490,inhibits |
| R6 | E5-ti-1 | T3 | objectOf | interleukin-2,inhibits |
| R7 | E5-ti-1 | T4 | subjectOf | interleukin-2,T-cell interleukin-2 |
| R8 | E4-ti-1 | T4 | objectOf | T-cell,T-cell interleukin-2 |
| R9 | E1-ab-1 | T5 | subjectOf | PG490,PG490 (triptolide |
| R10 | E2-ab-1 | T5 | objectOf | triptolide,PG490 (triptolide |
| R11 | E1-ab-2 | T6 | subjectOf | PG490,inhibits |
| R12 | E2-ab-2 | T6 | objectOf | interleukin,inhibits |
| R13 | E7-ab-2 | T7 | subjectOf | peripheral blood lymphocytes,human peripheral blood lymphocytes |
| R14 | E6-ab-2 | T7 | objectOf | human,human peripheral blood lymphocytes |
| R15 | E8-ab-2 | T8 | subjectOf | phorbol 12-myristate 13-acetate,stimulated |
| R16 | E3-ab-2 | T8 | objectOf | IL)-2,stimulated |
| R17 | E9-ab-2 | T9 | subjectOf | antibody,stimulated |
| R18 | E3-ab-2 | T9 | objectOf | IL)-2,stimulated |
| R19 | E2-ab-3 | T10 | subjectOf | PG490,inhibits |
| R20 | E4-ab-3 | T10 | objectOf | IL-2,inhibits |
| R21 | E1-ab-5 | T11 | subjectOf | PG490,inhibit |
| R22 | E2-ab-5 | T11 | objectOf | transcriptional activation,inhibit |
| R23 | E9-ab-6 | T12 | subjectOf | p65,activation |
| R24 | E4-ab-6 | T12 | objectOf | transcription factor,activation |
| R25 | E9-ab-7 | T13 | subjectOf | cyclosporin A,inhibit |
| R26 | E11-ab-7 | T13 | objectOf | IL-8,inhibit |
| R27 | E2-ab-8 | T14 | subjectOf | PG490,inhibition |
| R28 | E3-ab-8 | T14 | objectOf | cytokine,inhibition |
| R29 | E8-ab-8 | T15 | subjectOf | NF-kappaB,inhibition |
| R30 | E7-ab-8 | T15 | objectOf | transcriptional activation,inhibition |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-182 | Sentence | denotes | Immunosuppressant PG490 (triptolide) inhibits T-cell interleukin-2 expression at the level of purine-box/nuclear factor of activated T-cells and NF-kappaB transcriptional activation. |
| S2 | 183-290 | Sentence | denotes | PG490 (triptolide) is a diterpene triepoxide with potent immunosuppressive and antiinflammatory properties. |
| S3 | 291-526 | Sentence | denotes | PG490 inhibits interleukin(IL)-2 expression by normal human peripheral blood lymphocytes stimulated with phorbol 12-myristate 13-acetate (PMA) and antibody to CD3 (IC50 of 10 ng/ml), and with PMA and ionomycin (Iono, IC50 of 40 ng/ml). |
| S4 | 527-600 | Sentence | denotes | In Jurkat T-cells, PG490 inhibits PMA/Iono-stimulated IL-2 transcription. |
| S5 | 601-803 | Sentence | denotes | PG490 inhibits the induction of DNA binding activity at the purine-box/antigen receptor response element (ARRE)/nuclear factor of activated T-cells (NF-AT) target sequence but not at the NF-kappaB site. |
| S6 | 804-1003 | Sentence | denotes | PG490 can completely inhibit transcriptional activation at the purine-box/ARRE/NF-AT and NF-kappaB target DNA sequences triggered by all stimuli examined (PMA, PMA/Iono, tumor necrosis factor-alpha). |
| S7 | 1004-1196 | Sentence | denotes | PG490 also inhibits PMA-stimulated activation of a chimeric transcription factor in which the C-terminal TA1 transactivation domain of NF-kappaB p65 is fused to the DNA binding domain of GAL4. |
| S8 | 1197-1371 | Sentence | denotes | In 16HBE human bronchial epithelial cells, IL-8 expression is regulated predominantly by NF-kappaB, and PG490 but not cyclosporin A can completely inhibit expression of IL-8. |
| S9 | 1372-1635 | Sentence | denotes | The mechanism of PG490 inhibition of cytokine gene expression differs from cyclosporin A and involves nuclear inhibition of transcriptional activation of NF-kappaB and the purine-box regulator operating at the ARRE/NF-AT site at a step after specific DNA binding. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 0-36 | NP | denotes | Immunosuppressant PG490 (triptolide) |
| C2 | 145-181 | NP | denotes | NF-kappaB transcriptional activation |
| C3 | 183-201 | NP | denotes | PG490 (triptolide) |
| C4 | 291-296 | NP | denotes | PG490 |
| C5 | 396-433 | NP | denotes | phorbol 12-myristate 13-acetate (PMA) |
| C6 | 483-486 | NP | denotes | PMA |
| C7 | 546-551 | NP | denotes | PG490 |
| C8 | 601-606 | NP | denotes | PG490 |
| C9 | 804-809 | NP | denotes | PG490 |
| C10 | 1004-1009 | NP | denotes | PG490 |
| C11 | 1053-1084 | NP | denotes | a chimeric transcription factor |
| C12 | 1088-1093 | NP | denotes | which |
| C13 | 1240-1255 | NP | denotes | IL-8 expression |
| C14 | 1286-1295 | NP | denotes | NF-kappaB |
| C15 | 1301-1306 | NP | denotes | PG490 |
| C16 | 1352-1370 | NP | denotes | expression of IL-8 |
| C18 | 1526-1535 | NP | denotes | NF-kappaB |
| C17 | 1496-1535 | NP | denotes | transcriptional activation of NF-kappaB |
| R1 | C3 | C1 | coref-ident | PG490 (triptolide),Immunosuppressant PG490 (triptolide) |
| R2 | C4 | C3 | coref-ident | PG490,PG490 (triptolide) |
| R3 | C6 | C5 | coref-ident | PMA,phorbol 12-myristate 13-acetate (PMA) |
| R4 | C7 | C4 | coref-ident | PG490,PG490 |
| R5 | C8 | C7 | coref-ident | PG490,PG490 |
| R6 | C9 | C8 | coref-ident | PG490,PG490 |
| R7 | C10 | C9 | coref-ident | PG490,PG490 |
| R8 | C12 | C11 | coref-relat | which,a chimeric transcription factor |
| R9 | C15 | C10 | coref-ident | PG490,PG490 |
| R10 | C16 | C13 | coref-ident | expression of IL-8,IL-8 expression |
| R11 | C18 | C14 | coref-ident | NF-kappaB,NF-kappaB |
| R12 | C17 | C2 | coref-ident | transcriptional activation of NF-kappaB,NF-kappaB transcriptional activation |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-17 | other_organic_compound | denotes | Immunosuppressant |
| T2 | 18-23 | other_organic_compound | denotes | PG490 |
| T3 | 25-35 | other_organic_compound | denotes | triptolide |
| T4 | 46-66 | protein_molecule | denotes | T-cell interleukin-2 |
| T5 | 94-119 | protein_family_or_group | denotes | purine-box/nuclear factor |
| T6 | 123-140 | cell_type | denotes | activated T-cells |
| T7 | 145-154 | protein_complex | denotes | NF-kappaB |
| T8 | 183-188 | other_organic_compound | denotes | PG490 |
| T9 | 190-200 | other_organic_compound | denotes | triptolide |
| T10 | 207-227 | other_organic_compound | denotes | diterpene triepoxide |
| T11 | 291-296 | other_organic_compound | denotes | PG490 |
| T12 | 306-323 | protein_molecule | denotes | interleukin(IL)-2 |
| T13 | 338-379 | cell_type | denotes | normal human peripheral blood lymphocytes |
| T14 | 396-427 | other_organic_compound | denotes | phorbol 12-myristate 13-acetate |
| T15 | 429-432 | other_organic_compound | denotes | PMA |
| T16 | 450-453 | protein_molecule | denotes | CD3 |
| T17 | 483-486 | other_organic_compound | denotes | PMA |
| T18 | 491-500 | other_organic_compound | denotes | ionomycin |
| T19 | 530-544 | cell_line | denotes | Jurkat T-cells |
| T20 | 546-551 | other_organic_compound | denotes | PG490 |
| T21 | 561-564 | other_organic_compound | denotes | PMA |
| T22 | 581-585 | protein_molecule | denotes | IL-2 |
| T23 | 601-606 | other_organic_compound | denotes | PG490 |
| T24 | 633-653 | other_name | denotes | DNA binding activity |
| T25 | 661-772 | DNA_domain_or_region | denotes | purine-box/antigen receptor response element (ARRE)/nuclear factor of activated T-cells (NF-AT) target sequence |
| T26 | 788-802 | DNA_domain_or_region | denotes | NF-kappaB site |
| T27 | 804-809 | other_organic_compound | denotes | PG490 |
| T28 | 959-962 | other_organic_compound | denotes | PMA |
| T29 | 964-967 | other_organic_compound | denotes | PMA |
| T30 | 974-1001 | protein_molecule | denotes | tumor necrosis factor-alpha |
| T31 | 1004-1009 | other_organic_compound | denotes | PG490 |
| T32 | 1024-1027 | other_organic_compound | denotes | PMA |
| T33 | 1055-1084 | protein_family_or_group | denotes | chimeric transcription factor |
| T34 | 1098-1135 | protein_domain_or_region | denotes | C-terminal TA1 transactivation domain |
| T35 | 1139-1152 | protein_subunit | denotes | NF-kappaB p65 |
| T36 | 1169-1187 | protein_domain_or_region | denotes | DNA binding domain |
| T37 | 1191-1195 | protein_molecule | denotes | GAL4 |
| T38 | 1200-1238 | cell_type | denotes | 16HBE human bronchial epithelial cells |
| T39 | 1240-1244 | protein_molecule | denotes | IL-8 |
| T40 | 1286-1295 | protein_complex | denotes | NF-kappaB |
| T41 | 1301-1306 | other_organic_compound | denotes | PG490 |
| T42 | 1315-1328 | other_organic_compound | denotes | cyclosporin A |
| T43 | 1366-1370 | protein_molecule | denotes | IL-8 |
| T44 | 1389-1394 | other_organic_compound | denotes | PG490 |
| T45 | 1409-1422 | DNA_family_or_group | denotes | cytokine gene |
| T46 | 1447-1460 | other_organic_compound | denotes | cyclosporin A |
| T47 | 1474-1492 | other_name | denotes | nuclear inhibition |
| T48 | 1496-1522 | other_name | denotes | transcriptional activation |
| T49 | 1526-1535 | protein_complex | denotes | NF-kappaB |
| T50 | 1544-1564 | DNA_domain_or_region | denotes | purine-box regulator |
| T51 | 1582-1597 | DNA_domain_or_region | denotes | ARRE/NF-AT site |
| T52 | 1623-1634 | other_name | denotes | DNA binding |
metamap-sample
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 134-141 | C0039194 | denotes | -cells |
| T2 | 47-53 | C0039194 | denotes | -cell |
| T3 | 241-258 | C0021081 | denotes | mmunosuppressive |
| T4 | 1-18 | C0021081 | denotes | mmunosuppressant |
| T5 | 191-201 | C0077274 | denotes | riptolide) |
| T6 | 26-36 | C0077274 | denotes | riptolide) |
| T7 | 1545-1551 | C0220903 | denotes | urine- |
| T8 | 868-874 | C0220903 | denotes | urine- |
| T9 | 662-668 | C0220903 | denotes | urine- |
| T10 | 95-101 | C0220903 | denotes | urine- |
| T11 | 1497-1512 | C0040649 | denotes | ranscriptional |
| T12 | 587-600 | C0040649 | denotes | ranscription. |
| T13 | 156-171 | C0040649 | denotes | ranscriptional |
| T14 | 1345-1352 | C0018790 | denotes | nhibit |
| T15 | 1016-1023 | C0018790 | denotes | nhibits |
| T16 | 826-833 | C0018790 | denotes | nhibit |
| T17 | 608-616 | C0018790 | denotes | nhibits |
| T18 | 553-560 | C0018790 | denotes | nhibits |
| T19 | 298-306 | C0018790 | denotes | nhibits |
| T20 | 38-46 | C0018790 | denotes | nhibits |
| T21 | 1025-1028 | C0039654 | denotes | MA- |
| T22 | 562-565 | C0039654 | denotes | MA/ |
| T23 | 484-487 | C0039654 | denotes | MA |
| T24 | 1390-1395 | C0971326 | denotes | G490 |
| T25 | 1302-1307 | C0971326 | denotes | G490 |
| T26 | 1005-1010 | C0971326 | denotes | G490 |
| T27 | 805-810 | C0971326 | denotes | G490 |
| T28 | 602-607 | C0971326 | denotes | G490 |
| T29 | 547-552 | C0971326 | denotes | G490 |
| T30 | 292-297 | C0971326 | denotes | G490 |
| T31 | 186-189 | C0971326 | denotes | 90 |
| T32 | 19-24 | C0971326 | denotes | G490 |
| T33 | 1040-1050 | C1879547 | denotes | ctivation |
| T34 | 124-133 | C1879547 | denotes | ctivated |
| T35 | 114-120 | C1521761 | denotes | actor |
| T36 | 92-94 | C0332285 | denotes | f |
| T37 | 1552-1554 | C1533124 | denotes | ox |
| T38 | 875-878 | C1533124 | denotes | ox/ |
| T39 | 669-672 | C1533124 | denotes | ox/ |
| T40 | 102-105 | C1533124 | denotes | ox/ |
| T41 | 1475-1481 | C0521447 | denotes | uclear |
| T42 | 106-113 | C0521447 | denotes | uclear |
| T43 | 582-586 | C0879590 | denotes | L-2 |
| T44 | 54-67 | C0879590 | denotes | nterleukin-2 |
| T45 | 1583-1587 | C0600508 | denotes | RRE/ |
| T46 | 879-883 | C0600508 | denotes | RRE/ |
| T47 | 690-705 | C0600508 | denotes | esponse element |
| T48 | 879-883 | C0034788 | denotes | RRE/ |
| T49 | 673-689 | C0034788 | denotes | ntigen receptor |
| T50 | 1207-1212 | C0086418 | denotes | uman |
| T51 | 346-351 | C0086418 | denotes | uman |
| T52 | 969-973 | C0022020 | denotes | ono, |
| T53 | 566-570 | C0022020 | denotes | ono- |
| T54 | 503-507 | C0022020 | denotes | ono, |
| T55 | 492-501 | C0022020 | denotes | onomycin |
| T56 | 1287-1296 | C0079904 | denotes | F-kappaB, |
| T57 | 1140-1149 | C0079904 | denotes | F-kappaB |
| T58 | 894-903 | C0079904 | denotes | F-kappaB |
| T59 | 789-798 | C0079904 | denotes | F-kappaB |
| T60 | 1448-1461 | C0010592 | denotes | yclosporin A |
| T61 | 975-1002 | C1456820 | denotes | umor necrosis factor-alpha) |
| T62 | 307-318 | C0021764 | denotes | nterleukin( |
| T63 | 911-924 | C0162326 | denotes | NA sequences |
| T64 | 439-447 | C0021027 | denotes | ntibody |
| T65 | 834-860 | C0162493 | denotes | ranscriptional activation |
| T66 | 1424-1434 | C0185117 | denotes | xpression |
| T67 | 325-335 | C0185117 | denotes | xpression |
| T68 | 879-883 | C0003320 | denotes | RRE/ |
| T69 | 673-680 | C0003320 | denotes | ntigen |
| T70 | 1114-1129 | C0040624 | denotes | ransactivation |
| T71 | 1056-1064 | C0008109 | denotes | himeric |
| T72 | 208-217 | C0012780 | denotes | iterpene |
| T73 | 1410-1418 | C0079189 | denotes | ytokine |
| T74 | 1260-1269 | C0851285 | denotes | egulated |
| T75 | 1588-1593 | C0288011 | denotes | F-AT |
| T76 | 884-889 | C0288011 | denotes | F-AT |
| T77 | 714-749 | C0288011 | denotes | uclear factor of activated T-cells |
| T78 | 1576-1578 | C1516077 | denotes | t |
| T79 | 861-863 | C1516077 | denotes | t |
| T80 | 655-657 | C1516077 | denotes | t |
| T81 | 1029-1039 | C1948023 | denotes | timulated |
| T82 | 571-581 | C1948023 | denotes | timulated |
| T83 | 381-391 | C1948023 | denotes | timulated |
| T84 | 1334-1344 | C0205197 | denotes | ompletely |
| T85 | 815-825 | C0205197 | denotes | ompletely |
| T86 | 1065-1085 | C0040648 | denotes | ranscription factor |
| T87 | 1419-1434 | C0017262 | denotes | ene expression |
| T88 | 1624-1635 | C1148673 | denotes | NA binding. |
| T89 | 904-910 | C1521840 | denotes | arget |
| T90 | 758-764 | C1521840 | denotes | arget |
| T91 | 1312-1315 | C1518422 | denotes | ot |
| T92 | 778-781 | C1518422 | denotes | ot |
| T93 | 950-958 | C0332128 | denotes | xamined |
| T94 | 1604-1608 | C1261552 | denotes | tep |
| T95 | 1566-1575 | C3242339 | denotes | perating |
| T96 | 280-290 | C0871161 | denotes | roperties. |
| T97 | 1213-1239 | C1711178 | denotes | ronchial epithelial cells, |
| T98 | 925-937 | C1444748 | denotes | riggered by |
| T99 | 1556-1565 | C1704735 | denotes | egulator |
| T100 | 765-773 | C1519249 | denotes | equence |
| T101 | 942-948 | C0234402 | denotes | timuli |
| T102 | 799-803 | C0205145 | denotes | ite. |
| T103 | 475-478 | C1515981 | denotes | nd |
| T104 | 1157-1162 | C0699952 | denotes | used |
| T105 | 1192-1196 | C1416832 | denotes | AL4. |
| T106 | 1377-1386 | C0441712 | denotes | echanism |
| T107 | 1130-1136 | C1880389 | denotes | omain |
| T108 | 263-279 | C1515999 | denotes | ntiinflammatory |
| T109 | 1615-1623 | C0205369 | denotes | pecific |
| T110 | 451-454 | C3542405 | denotes | D3 |
| T111 | 1410-1423 | C1333196 | denotes | ytokine gene |
| T112 | 517-519 | C0439509 | denotes | 0 |
| T113 | 1099-1109 | C1707271 | denotes | -terminal |
| T114 | 352-380 | C1518997 | denotes | eripheral blood lymphocytes |
| T115 | 339-345 | C0439166 | denotes | ormal |
| T116 | 1150-1153 | C3540646 | denotes | 65 |
| T117 | 1110-1113 | C1539908 | denotes | A1 |
| T118 | 234-240 | C3245505 | denotes | otent |
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 974-979 | HP_0002664 | denotes | tumor |
Anatomy-MAT
| Id | Subject | Object | Predicate | Lexical cue | mat_id |
|---|---|---|---|---|---|
| T1 | 362-367 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/MAT_0000083|http://purl.obolibrary.org/obo/MAT_0000315 |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 429-432 | Disease | denotes | PMA | http://purl.obolibrary.org/obo/MONDO_0016692|http://purl.obolibrary.org/obo/MONDO_0018687 |
| T3 | 483-486 | Disease | denotes | PMA | http://purl.obolibrary.org/obo/MONDO_0016692|http://purl.obolibrary.org/obo/MONDO_0018687 |
| T5 | 561-564 | Disease | denotes | PMA | http://purl.obolibrary.org/obo/MONDO_0016692|http://purl.obolibrary.org/obo/MONDO_0018687 |
| T7 | 959-962 | Disease | denotes | PMA | http://purl.obolibrary.org/obo/MONDO_0016692|http://purl.obolibrary.org/obo/MONDO_0018687 |
| T9 | 964-967 | Disease | denotes | PMA | http://purl.obolibrary.org/obo/MONDO_0016692|http://purl.obolibrary.org/obo/MONDO_0018687 |
| T11 | 974-979 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
| T12 | 1024-1027 | Disease | denotes | PMA | http://purl.obolibrary.org/obo/MONDO_0016692|http://purl.obolibrary.org/obo/MONDO_0018687 |
NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 345-350 | OrganismTaxon | denotes | human | 9606 |
| T2 | 1206-1211 | OrganismTaxon | denotes | human | 9606 |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T1 | 46-52 | Body_part | denotes | T-cell | http://purl.obolibrary.org/obo/CL_0000084 |
| T2 | 362-379 | Body_part | denotes | blood lymphocytes | http://purl.obolibrary.org/obo/CL_4030029 |
| T3 | 1212-1238 | Body_part | denotes | bronchial epithelial cells | http://purl.obolibrary.org/obo/CL_0002328 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T1 | 974-979 | Phenotype | denotes | tumor | HP:0002664 |
CL-cell
| Id | Subject | Object | Predicate | Lexical cue | cl_id |
|---|---|---|---|---|---|
| T1 | 46-52 | Cell | denotes | T-cell | http://purl.obolibrary.org/obo/CL:0000084 |
| T2 | 133-140 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T3 | 351-379 | Cell | denotes | peripheral blood lymphocytes | http://purl.obolibrary.org/obo/CL:4030030 |
| T4 | 537-544 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T5 | 741-748 | Cell | denotes | T-cells | http://purl.obolibrary.org/obo/CL:0000084 |
| T6 | 1212-1238 | Cell | denotes | bronchial epithelial cells | http://purl.obolibrary.org/obo/CL:0002328 |