The Texas A&M University Biosafety Level 2, air-conditioned 16.14 m3, ¾ scale physical particle test room operated at an air exchange rate of 6 air changes per hour (ACH) was utilized to test PRD1 phages as SARS-CoV-2 simulants. Twelve PM2.5 filter samplers at 15 L/min air flow were used to collect the aerosolized virus (Figure 4 and Figure 5) [31]. Tests were conducted using three different ventilation configurations: (a) with the air inlet in the ceiling on the left, exhaust on the right; (b) with the air inlet in the ceiling above the bed, exhaust at the bottom left on the wall; and (c) with the air inlet in the ceiling above the bed, exhaust at the bottom left on the wall, air curtain entry/door (Figure 5).