Scores of the first five NPs were not statistically different between demented and non-demented subjects (data not shown). However, among non-demented subjects, subjects who had mild cognitive impairment (GDS 3, n = 11) had significantly lower NP2 score than that of cognitively intact subjects (GDS 1–2, n = 12, p = 0.002), but not for other NPs. The difference remained statistically significant after an adjustment for sex, education, hypertension, diabetes, and presence of APOE ε4 allele (p = 0.004).