a  Comparisons between subjects whose Global Deterioration Scale (GDS) = 1–3 (non-demented) and GDS = 4–7 (demented) using Student's t-test for continuous variables and Fisher's exact test for categorical variables.
b  Body mass index (BMI) cannot be calculated for a double amputee whose GDS = 5.
c  All subjects who carried an ε2 or ε4 allele were ε2/ε3 or ε3/ε4 except one subject with GDS = 4 who was an ε2/ε4.