Characteristic   All subjects (n = 47)   GDS 1-3 (n = 23)   GDS 4–7 (n = 24)   P-valuea
Age in years, mean (SD)  102.2 (2.5)  102.2 (2.3)  102.2 (2.8)  0.946
Female, n (%)  42 (89%)  19 (83%)  23 (96%)  0.188
Race, n (%)     0.348
  Caucasian  42 (89%)  22 (96%)  20 (83%)
  Black  5 (11%)  1 (4%)  4 (17%)
BMI in kg/m2, mean (SD)b  22.1 (3.9)  23.1 (3.5)  21.0 (4.0)  0.067
Hypertension, n (%)  25 (53%)  12 (52%)  13 (54%)  1
Diabetes, n (%)  3 (6%)  2 (9%)  1 (4%)  0.609
Education, n (%)     0.204
   < High school  23 (51%)  9 (39%)  14 (64%)
  High school  12 (27%)  7 (30%)  5 (23%)
  > High school  10 (22%)  7 (30%)  3 (14%)
  No data  2  0  2
Living, n (%)     0.212
  Community dwelling  14 (30%)  9 (39%)  5 (21%)
  Institutionalized  33 (70%)  14 (61%)  19 (79%)
Dietary supplement use, n (%)  34 (72%)  14 (61%)  20 (83%)  0.111
Medications, n (%)
  Antidepressants  14 (30%)  4 (17%)  10 (42%)  0.111
  Antipsychotics  5 (12%)  1 (4%)  4 (17%)  0.348
  Anti-inflammatory medications  5 (12%)  4 (17%)  1 (4%)  0.188
  Antithrombotics  10 (21%)  5 (22%)  5 (21%)  1
  Antibiotics  7 (15%)  2 (9%)  5 (21%)  0.416
Smoking, n (%)     0.570
  Never  30 (86%)  18 (86%)  12 (86%)
  Past  4 (11%)  3 (14%)  1 (7%)
  Present  1 (3%)  0 (0%)  1 (7%)
  No data  12  2  10
Alcohol use, n (%)     0.041
  Never  21 (60%)  9 (43%)  12 (86%)
  Past  6 (17%)  5 (24%)  1 (7%)
  Present  8 (23%)  7 (33%)  1 (7%)
  No data  12  2  10
APOE, n (%)c
  ε2 allele carrier  8 (17%)  3 (13%)  5 (21%)  0.701
  ε4 allele carrier  8 (17%)  3 (13%)  5 (21%)  0.701