Due to multiple identifier systems used by different databases for the same entities, we utilized the Data Translator Node Normalization API (https://github.com/TranslatorIIPrototypes/NodeNormalization) for data integration. COVID-KOP is powered by the knowledge graph database Neo4J (https://neo4j.com/), which uses Cypher to enable complex graph database queries. The fully integrated COVID-KOP KG can be mined in the same way as ROBOKOP KG (Bizon et al., 2019).