Critical-illness polyneuropathy (CIP) Acute neuropathy or CIP may develop in patients suffering a number of severe illnesses. CIP typically remits as the patient recovers from the illness [44]. Signs and symptoms of CIP include reduced compound muscle action potentials amplitude, abnormal spontaneous unilateral activities in the diaphragmatic needle electromyography evaluation, abnormal F responses, and an abnormal H reflex on electrodiagnostic studies [106]. The pathogenesis of CIP is not well elucidated and may involve a systemic inflammatory response to sepsis that damages the nerves [107]. Its prevalence among COVID-19 patients is not known.