SARS broke out in Hong Kong, Taiwan, Canada, and other locations in 2003. It has been reported to be associated with encephalitis, ischemic stroke, and polyneuropathy [35]. Seizures have been mentioned as the first symptom of SARS-related encephalitis [36]. In a necropsy study of eight patients who died of SARS, there was evidence of SARS-CoV infection in the brain cortex and hypothalamus [37]. Particles from the SARS-CoV virus have been found in the brains of patients infected with SARS, most frequently in brain neurons [37–39]. Murine studies found that intranasal injections of both MERS-CoV and SARS-CoV could enter the brain, presumably via the olfactory nerves [40,41]. Among the areas of the brain infected, the brain stem was a primary, but not exclusive, target for both MERS-CoV [41] and SARS-CoV [40,42].