Estimating the reproduction number under interventions Figure 4 shows the model prediction for the reproduction (‘R’) number over time until 11 May 2020, when lockdown measures were relaxed. All interventions (social distancing, school closures/lockdown) had a significant impact on the reproductive number for COVID-19 in the SW. We predict that prior to any interventions R was 2.6 (95% CrI 2.0 to 3.2), and the introduction of social distancing reduced this number to 2.3 (95% CrI 1.8 to 2.9). At the minimum, R was 0.6 (95% CrI 0.5 to 0.7) after all prior interventions were enacted and adhered to (social distancing, school closures and lockdown). Figure 4 The effect of interventions on estimates of R (y-axis) over time until 11 May 2020. Additional results for the fitting performance of the model (online supplemental figure S2A, B and table S2), the performance based on prior data (online supplemental figure S3A–D) and sensitivity analysis can be found in the online supplemental information.