Drive-through mass vaccination facilities can be designed and implemented in various shapes and sizes [7,19,21,22,23]. Drive-through facilities with more dispensing lanes can provide higher throughputs and prevent traffic overflow onto neighboring streets [10,24]. Drive-through facilities need to be staffed with different skills including immunization, nursing, admin, IT, logistics, and security. Drive-through clinics can be set to work 24 h a day in two, three, or four shifts. Although drive-throughs have lower disease transmission risks, especially when staff and visitors use personal protective equipment and are vaccinated before vaccinating others, attention must be paid to the safety and the security issues related to traffic, drivers’ behaviors, and extreme weather conditions. Hence, large drive-through clinics may need to be supported by local emergency services such as police, fire, and paramedics [18,25,26].