Arrhythmia during hospitalization for COVID-19 was associated with increased in-hospital mortality in the univariate analysis. However, in multiple regression analyses, pre-existent cardiovascular disease had a stronger prognostic implication than incident cardiac arrhythmia regarding this aspect, even though the majority of fatal cases were due to respiratory failure. This is in line with observations from large multicenter cohorts identifying risk factors for in-hospital death in COVID-19 [28]. With respect to a wide range of symptoms and prognostic severity associated with an infection with SARS-CoV-2, further studies aiming at individualized risk stratification are crucial.