With respect to clinical outcome, an association of incident arrhythmia with the need for ICU/IMC-care was identified, which is in line with the previous observations from Pennsylvania [8]. However, age and cardiac co-morbidities have been identified as potential confounders in our analyses regarding ICU/IMC admission. Furthermore, rates of NIV- or high-flow oxygen-therapy and need for vasopressors were increased in this group. These observations, together with the results from biomarker analyses, reflect an association of the severity of disease with the incidence of cardia arrhythmia in our cohort.