The key to successfully contain the spread of an unexpected disease like COVID-19 is to understand the complicated two-way interaction between the dynamics of disease and those of information (and the human behavior response to information) [7]. Information might either amplify or diminish the public’s response to a risk event, depending on the transmission of risk information and public’s reactions at the time it occurs [8]. At the micro-level, one’s behavior depends on the epidemiological status of the disease, the individual’s knowledge about it (information accessed), misinformation, and the individual’s education and income level [9]. Along with the spread of disease in social life (physical level), information spreads in a virtual network, which brings the awareness of crisis for people [10,11,12], leading them to take preventive measures to stay healthy [13,14]. Therefore, the spread of disease facilitates the spread of information, which in turn inhibits the spread of disease [15,16]. However, on the other hand, people usually get illogical, fail to discern falsity, and disregard the truth during information dissemination [17,18]. Misleading information seems to have a natural disposition to resonate with public opinions, which causes spontaneous misrepresentation in transmission [19]. In addition, discussions on epidemic bring panic [20] and aggravate the harm of the epidemic [21], which will be further exaggerated by social media [22]. Meanwhile, increasing uncertainty about the disease makes people feel loss of control and boost people’s anxiety [23], usually accompanied by psychological distress [24]. Therefore, information is critical to fighting against the COVID-19-crisis [25,26], and improper information management strategy may lead to systematic failure [27].