Spike protein + rutin Interacting residue H-bond distance (Å) H-bond (D-H--A) Hydrophobic residues His 49.A NE2–Rutin.het O15 3.28 HNE2-H--O15 Ser50, Thr51, Ser967, Ser968 GLN 52.A OE1–Rutin.het O14 2.89 HOE1-H--O14   THR 274.A OG1–Rutin.het O14 3.30 HOG1-H--O14   ASN 969.A ND2–Rutin.het O10 3.17 HND2-H--O10   PHE 970.A N–Rutin.het O9 3.10 HN-H--O9