2.1.3.  CNS diseases
Another significant growing healthcare need with a major economic and medical impacts is Dementia [19]. Globally, dementia affects around 50 million people, and over the past 18 years, the percentage of death among Alzheimer’s patients doubled while deaths resulting from stroke, and heart diseases have decreased [20]. In the US alone the number of Alzheimer’s dementia cases is expected to shoot up to 13.8 million and impose a health care burden of 1.1 trillion dollars by 2050 [20]. As of today, there are no medications known to reverse the progression of Alzheimer’s disease [21].