According to the American College of Emergency Physicians, fever is the most commonly encountered chief complaint to the emergency department in the United States, accounting for 15% of visits [1]. The recent outbreak of coronavirus disease 2019 (COVID-19) in the US and across the world has resulted in global catastrophe with innumerable deaths and hospitalizations. COVID-19 is asymptomatic in a number of children, and its varied manifestations are still being elucidated. Cheilitis has not been previously described as a clinical presentation of COVID-19. Cheilitis refers to the inflammation of the lips causing a dry, cracked appearance. It is found on the peri-oral region, vermilion border, or labial mucosa. There are many different types of this condition, such as cheilitis simplex, angular, contact, exfoliative, drug-induced, actinic, glandular, and plasma cell [2]. The most common type is cheilitis simplex that is characterized by the dry, cracked appearance with peeling of the lips, which occurs due to a lack of moisture due to excessive lip licking or smacking [3]. We describe a patient with fever and cheilitis diagnosed with clinical pneumonia in the setting of COVID-19 infection.