CI 0.09 to 0.89). According to the type of mask used, there were differences in headache intensity, and the impact of a headache in the subjects who used a filter mask was worse in all the aspects evaluated. Conclusion The appearance of ‘de novo’ headache is associated with the use of filter masks and is more frequent in certain healthcare workers, causing a greater occupational, family, personal and social impact. Key messages What is already known about this subject? During the increase in COVID-19 cases, health authorities established the mandatory use of Personal Protective Equipment (PPE) by health professionals. Face masks are recommended as a simple barrier to help prevent respiratory droplets from travelling through the air and reaching others when the person wearing the mask coughs, sneezes, speaks or raises his voice. In ‘front-line’ work, wearing masks can be time consuming. Although highly effective masks are generally well tolerated, some health problems have been reported, including headaches. What are the new findings? The appearance of ‘de novo’ headache is associated with the use of filter masks and is more f