nib) for drug like properties and leadlikeness. Properties   1 2 3 4 5 6 LL 1   –0.669 0.631 0.858 –0.51 –0.066 clog Pc 2 –0.669   –0.754 –0.912 –0.173 –0.372 clogS 3 0.631 –0.75