8.  Anaferine  –5.13  174.99 µM  Glu290, Cys128, Lys5, Gln127, Tyr126, Lys137  –5.7  66.02 µM  Cys145, Asn142, Leu141, Phe140,Glu166, Ser144,His172,Met165, His164, Gln189, Asp187, Arg188, Met49, His41  –76.27  –67.75  –8.52  0  Thr25, Thr26, Leu27, Cys145, His163, Met165, Glu166,His172, Phe140, Leu141,Ser144, Gly143