2.  Withanolide A  –5.26  139.0 µM  Lys5, Gln127, Tyr126, Val125, Ser139, Lys137, Glu288, Glu290  –8.5  592.38 nM  Asp289, Thr199, Glu290, Arg131, Lys137, Tyr239, Leu272, Leu287, Leu286, Met276, Gly275  –91.61  –70.18  –21.43  0  Gly179, Asn180, Phe181, Asn84, Cys85, Arg40, Phe185, Tyr54, Asn53, Pro52, Arg188