1.  Withaferin A  –2.85  8.21 mM  Tyr126, Gln127, Gly138, Va171, Gly170, Lys137, Lys5  –8.4  670.89 nM  Arg105, Ile106, Val104, Ser158, Phe294,Phe112, Phe8, Thr111, Asp295, Asn151,Gln110, Thr292, Gln107  –98.51  –78.64  –19.87  0  Gly143, Ser144, Cys145, His163, Met165, Glu166, Gln189, Thr190, Asn142, Leu141, Phe140