10.  Procainamide  –5.03  206.96 µM   Glu161, Asn109, Leu162, Asp108, Gly160, Gln269, Cys270  –6.3  24.06 µM  Asn109, Gln269, Leu162, Val159, His89, Asp108, Glu161, Gly160  –76.81  –66.66  –10.15  0   Leu162, Glu161, Gly160, Gln269,Asp108, Asn109,Cys270