Withasomnine  –5.56  84.41 µM  Asn109, Gln269, Cys270, Leu162, Gly160, Cys270  –7.2  4.50 µM  Asp76, Pro59, Phe79, Leu80, Thr74, Ala68, Thr75, Arg65, Pro77, Leu58  –69.24  –69.24  0  0   Asp76, Pro77, Thr75, Leu80, Leu58, Pro59, Arg65