rg166  –75.28  –68.35  –6.93  0  Ala68, Thr74, Phe79, Asp76, Pro77, Lys43, Arg65, Pro59, Leu58
9.  Withasomnine  –5.56  84.41 µM  Asn109, Gln269, Cys270, Leu1