60, Val159, Thr158, His89  –10.1  38.9 nM   Thr158, His89, Glu161, Gly160, Asn109, Gln269, Leu162, Val159  –99.07  –91.72  –7.35  0  Pro59, Ala68, Arg65, Phe69, Thr74, Thr7