4.  Withanolide D  –9.56  98.21 nM  Gly160, Glu161, Asn109, Gln269, Cys270, Leu162, Cys160, Val159, Thr158, His89  –10.1  38.9 nM   Thr158, His89, Glu161, Gly160, Asn109, Gln269, Leu162, Val159  –99.07  –91.72  –7.35  0  Pro59, Ala68, Arg65, Phe69, Thr74, Thr75, Pro77, Ile44, Lys45, Pro46, Met23, His47, Asn48