5.  Withanolide E  –6.94  8.17 µM  Gln957, Lys964, Lys304, Leu303, Thr302  –8.0  771.57 nM  Asn30, Phe59, Thr33, Phe58, Phe306, Val289, Ala288, Lys300, Ser297, Leu296, Leu293, Asp294  –91.24  –82.26  –8.98  0  Glu340, Gly339, Phe338, Cys336, Ala363, Asp364, Val362, Leu335