5.  Withanolide E  –7.13  5.93 µM  Thr980, Gly981, Gln984, Arg977, Tyr738, Leu983  –9.5  99.21 nM   Lys715, Ala753, Ser750, Pro844, Thr302, Leu843, Ala633,Gln599, Ile652, Leu597, Val581, Ile299, Pro651, Ile650, Tyr300, Ala754  –99.34  –93.84  –5.49  0  Leu597,Ala633, Gln599, Ile652, Val581, Pro651, Thr302, Ile650, Tyr300, Ile299, Pro844, Leu843, Lys715, Ser750, Ala753, Ala754