, Glu452, Asp454, Ser456, Arg449, Arg441, Val458, Pro459, Arg444, His445, Phe460, Pro466, Gly464, Ser461, Lys465   
2.  Withanolide A  –9.78  67.23 nM  Gln984,Leu983, Thr980, Gly981, Arg977, Phe952, Tyr7