22, Pro407  –86.22  –73.55  –12.67  0  Phe391, His410, Glu411, His387, Trp357, Ala356, Ser355, Ala354, His353, Asn66, Ala63, Tyr62, Val518, Tyr523   
11.  Losartan  –6.72  11.86 µM   Asn406, Met223, Arg522, Pro407, Gly404, Glu403, His410, Glu411, Tyr523, Phe391, His387, Ala356, Val518  –9.4  129.59 nM  Met223, Pro519, Arg522, His410, His387, Tyr523, Glu411, Ser355, Val518, Ala3