8.  Anaferine  –8.25  890.86 nM  Glu411, Tyr523, His383, His387, Glu384, Val380, Ala356, Ser355, Ala354, His353  –6.7  12.50 µM  His383, His387, Ala354, Glu384, Ser355, Ala356, Val518, His513, Phe512, His353, Tyr523, Tyr520, Gln281, Phe457, Phe527  –77.85  –74.35  –3.5  0  Phe570, Met223, Asn406, Glu403, Gly404, Pro407, His410, Phe391, Glu411, His387