2.  Withanolide A  –10.13  37.44 nM  Asp453, Thr282, Gln281, Phe457, Glu376, Val379, Val380, Asp415, His383, Glu384, Ala354, His353, His387, Glu411, His513, Phe512, Tyr523  –10.6  15.57 nM  His410, Ala353, His387, Trp357, Phe391, Asn66, Asn70, Ser516, Glu143, Phe512, Val518, His353, Ser355, His513, Tyr523, Glu411, Arg522  –98.26  –78.36  –19.90  0  Leu375, Lys449, Tyr287, Ser298, Met299, Asp300, Thr301, Thr302