droxychloroquine, Oberadilol, Poziotinib). Physicochemical properties S. No. Ligands Lipinski’s rule of 5 parameters % Absorption(>50%)a Topological polar surface area (Å)2(TPSA)b(<160 Å) MW (<500) clog Pc(<5) Hydrogen bond donors(NOHNH)(≤5) Hydrogen bond acceptors(NON)≤10) Number of rotatable bonds(≤10) L