PMC:7736111 / 9717-10287 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7736111","sourcedb":"PMC","sourceid":"7736111","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7736111","text":"s (PRRs; Leiva-Juárez et al., 2018). ATII cells are known to express key endogenous PRRs like Toll-like receptors (TLRs), cyclic GMP–AMP synthase (cGAS); and retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs). Among these, cytosolic RLRs and endosomal TLRs (TLR3, TLR7, TLR8, TLR9) have a prominent role in initiating the antiviral response by sensing RNA from SARS-CoVs (Lester and Li, 2014; Chan and Gack, 2016).\nRLRs are a complex of sensor proteins that include RIG-I, melanoma differentiation-associated gene 5 (MDA5), and the more recently discovered pro","tracks":[{"project":"LitCovid-PD-HP","denotations":[{"id":"T8","span":{"begin":483,"end":491},"obj":"Phenotype"}],"attributes":[{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0002861"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"174","span":{"begin":122,"end":145},"obj":"Gene"},{"id":"175","span":{"begin":158,"end":188},"obj":"Gene"},{"id":"176","span":{"begin":268,"end":272},"obj":"Gene"},{"id":"177","span":{"begin":274,"end":278},"obj":"Gene"},{"id":"178","span":{"begin":280,"end":284},"obj":"Gene"},{"id":"179","span":{"begin":286,"end":290},"obj":"Gene"},{"id":"182","span":{"begin":371,"end":380},"obj":"Species"},{"id":"183","span":{"begin":190,"end":195},"obj":"Gene"},{"id":"238","span":{"begin":476,"end":481},"obj":"Gene"},{"id":"239","span":{"begin":483,"end":525},"obj":"Gene"},{"id":"240","span":{"begin":527,"end":531},"obj":"Gene"}],"attributes":[{"id":"A174","pred":"tao:has_database_id","subj":"174","obj":"Gene:115004"},{"id":"A175","pred":"tao:has_database_id","subj":"175","obj":"Gene:23586"},{"id":"A176","pred":"tao:has_database_id","subj":"176","obj":"Gene:7098"},{"id":"A177","pred":"tao:has_database_id","subj":"177","obj":"Gene:51284"},{"id":"A178","pred":"tao:has_database_id","subj":"178","obj":"Gene:51311"},{"id":"A179","pred":"tao:has_database_id","subj":"179","obj":"Gene:54106"},{"id":"A182","pred":"tao:has_database_id","subj":"182","obj":"Tax:694009"},{"id":"A183","pred":"tao:has_database_id","subj":"183","obj":"Gene:23586"},{"id":"A238","pred":"tao:has_database_id","subj":"238","obj":"Gene:23586"},{"id":"A239","pred":"tao:has_database_id","subj":"239","obj":"Gene:64135"},{"id":"A240","pred":"tao:has_database_id","subj":"240","obj":"Gene:64135"},{"subj":"174","pred":"source","obj":"LitCovid-PubTator"},{"subj":"175","pred":"source","obj":"LitCovid-PubTator"},{"subj":"176","pred":"source","obj":"LitCovid-PubTator"},{"subj":"177","pred":"source","obj":"LitCovid-PubTator"},{"subj":"178","pred":"source","obj":"LitCovid-PubTator"},{"subj":"179","pred":"source","obj":"LitCovid-PubTator"},{"subj":"182","pred":"source","obj":"LitCovid-PubTator"},{"subj":"183","pred":"source","obj":"LitCovid-PubTator"},{"subj":"238","pred":"source","obj":"LitCovid-PubTator"},{"subj":"239","pred":"source","obj":"LitCovid-PubTator"},{"subj":"240","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T52","span":{"begin":37,"end":219},"obj":"Sentence"},{"id":"T53","span":{"begin":220,"end":424},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T52","pred":"source","obj":"LitCovid-sentences"},{"subj":"T53","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-HP","color":"#93a1ec","default":true},{"id":"LitCovid-PubTator","color":"#bbec93"},{"id":"LitCovid-sentences","color":"#ec93d5"}]}]}}