13  • Decrease in total lymphocyte count while increase in neutrophil count was observed in ICU patients.• Higher plasma levels of IL-2, IL-7, IL-10, GCSF, IP-10 (CXCL10), CCL2, CCL3, and TNF-α were observed in ICU patients as compared to non-ICU.• Increased levels of TH2 cytokine IL-4 was reported.• Increased levels of D-dimer, ALT, and AST in ICU patients.