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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7736111","sourcedb":"PMC","sourceid":"7736111","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7736111","text":"COVID-19: The Emerging Immunopathological Determinants for Recovery or Death\n\nAbstract\nHyperactivation of the host immune system during infection by SARS-CoV-2 is the leading cause of death in COVID-19 patients. It is also evident that patients who develop mild/moderate symptoms and successfully recover display functional and well-regulated immune response. Whereas a delayed initial interferon response is associated with severe disease outcome and can be the tipping point towards immunopathological deterioration, often preceding death in COVID-19 patients. Further, adaptive immune response during COVID-19 is heterogeneous and poorly understood. At the same time, some studies ","divisions":[{"label":"article-title","span":{"begin":0,"end":76}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"2","span":{"begin":0,"end":8},"obj":"Disease"},{"id":"3","span":{"begin":71,"end":76},"obj":"Disease"},{"id":"19","span":{"begin":149,"end":159},"obj":"Species"},{"id":"20","span":{"begin":202,"end":210},"obj":"Species"},{"id":"21","span":{"begin":236,"end":244},"obj":"Species"},{"id":"22","span":{"begin":553,"end":561},"obj":"Species"},{"id":"27","span":{"begin":136,"end":145},"obj":"Disease"},{"id":"28","span":{"begin":193,"end":201},"obj":"Disease"},{"id":"29","span":{"begin":544,"end":552},"obj":"Disease"},{"id":"30","span":{"begin":604,"end":612},"obj":"Disease"}],"attributes":[{"id":"A2","pred":"tao:has_database_id","subj":"2","obj":"MESH:C000657245"},{"id":"A3","pred":"tao:has_database_id","subj":"3","obj":"MESH:D003643"},{"id":"A19","pred":"tao:has_database_id","subj":"19","obj":"Tax:2697049"},{"id":"A20","pred":"tao:has_database_id","subj":"20","obj":"Tax:9606"},{"id":"A21","pred":"tao:has_database_id","subj":"21","obj":"Tax:9606"},{"id":"A22","pred":"tao:has_database_id","subj":"22","obj":"Tax:9606"},{"id":"A27","pred":"tao:has_database_id","subj":"27","obj":"MESH:D007239"},{"id":"A28","pred":"tao:has_database_id","subj":"28","obj":"MESH:C000657245"},{"id":"A29","pred":"tao:has_database_id","subj":"29","obj":"MESH:C000657245"},{"id":"A30","pred":"tao:has_database_id","subj":"30","obj":"MESH:C000657245"},{"subj":"2","pred":"source","obj":"LitCovid-PubTator"},{"subj":"3","pred":"source","obj":"LitCovid-PubTator"},{"subj":"19","pred":"source","obj":"LitCovid-PubTator"},{"subj":"20","pred":"source","obj":"LitCovid-PubTator"},{"subj":"21","pred":"source","obj":"LitCovid-PubTator"},{"subj":"22","pred":"source","obj":"LitCovid-PubTator"},{"subj":"27","pred":"source","obj":"LitCovid-PubTator"},{"subj":"28","pred":"source","obj":"LitCovid-PubTator"},{"subj":"29","pred":"source","obj":"LitCovid-PubTator"},{"subj":"30","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T1","span":{"begin":0,"end":9},"obj":"Sentence"},{"id":"T2","span":{"begin":10,"end":76},"obj":"Sentence"},{"id":"T3","span":{"begin":78,"end":86},"obj":"Sentence"},{"id":"T4","span":{"begin":87,"end":211},"obj":"Sentence"},{"id":"T5","span":{"begin":212,"end":359},"obj":"Sentence"},{"id":"T6","span":{"begin":360,"end":562},"obj":"Sentence"},{"id":"T7","span":{"begin":563,"end":652},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T1","pred":"source","obj":"LitCovid-sentences"},{"subj":"T2","pred":"source","obj":"LitCovid-sentences"},{"subj":"T3","pred":"source","obj":"LitCovid-sentences"},{"subj":"T4","pred":"source","obj":"LitCovid-sentences"},{"subj":"T5","pred":"source","obj":"LitCovid-sentences"},{"subj":"T6","pred":"source","obj":"LitCovid-sentences"},{"subj":"T7","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#ecae93","default":true},{"id":"LitCovid-sentences","color":"#9493ec"}]}]}}