PMC:7712180 / 38845-39233
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1314 | 81-84 | Gene | denotes | K81 | Gene:3887 |
| 1317 | 325-334 | Species | denotes | HCoV-OC43 | Tax:31631 |
| 1326 | 163-169 | Disease | denotes | Sia C1 | MESH:C565170 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T219 | 0-388 | Sentence | denotes | Substitutions of N27 having an H-bond with OA9 of the 9-O-acetyl carbonyl group, K81 forming H-bonds with O1 and N5 of Sia, or S83 containing an H-bond with O3 of Sia C1, with alanine and mutations of L80, L86 or W90 in hydrophobic pockets accommodating the 5-N-acyl moiety and the 9-O-acetyl-methyl moiety provided a mutant HCoV-OC43 S1A that had lost the ability to bind to 9-O-Ac-6SLN. |