Wild types of both Yamagata (HA with F95 and N194) and Victoria (HA with G141, R162 and D196) lineages: Neu5Acα2,6Gal>Neu5Acα2,3Gal2001–2007 clinical isolates in Taiwan:83% of Yamagata-like strains prefer α2,6Sia; 17% prefer both α2,3Sia and α2,6Sia. 54% of Victoria-like strains prefer both α2,3Sia and α2,6Sia; 25% prefer sulfated glycan, either β-Gal-3-sulfate or 6-HSO3-Galβ1,4GlcNAc; 21% prefer α2,6Sia.Dual α2,3Sia and α2,6Sia-binding viruses seem to be associated with bronchopneumonia and gastrointestinal symptoms.