The patient who self-quarantined at home, despite presenting with similar onset symptoms, experienced a mild course of infection of shorter duration. The nasopharyngeal swab test was performed when the person was already asymptomatic. This patient was the only one on everolimus due to a high number of Epstein-Barr virus copies. Although there are speculations about this drug’s antiviral activity in relation to SARS-CoV-2, no conclusions can be drawn from a single case. Some authors claim a possible beneficial effect for everolimus as therapy for COVID-19 due to its immunomodulatory activity [27]. Moreover, the anti-replicative effect of controlling the spread of Epstein–Barr virus or cytomegalovirus can also be promising in SARS-CoV-2 infection on the basis of its ability to reduce mRNA translation, ribosome biogenesis, protein synthesis, mitochondrial metabolism and viral replication.