Our adopted strategy for immunosuppressive therapy comprised a median reduction of 50% (IQR 40–80) of cyclosporine doses and 50% (IQR 13–69) of mycophenolate. In all hospitalized patients, a 0.5–1 mg/kg/day bolus of prednisone was administered for the first 7 days. Those intubated or in serious condition were given an equivalent intravenous dose of methylprednisolone. Progressive tapering then followed, leading to a low maintenance dose of 5–10 mg/day at discharged. Immunosuppressive therapy remained reduced until the first outpatient follow-up examination. At that time, the original immunosuppressive regime was resumed and corticosteroid therapy was discontinued. No graft rejection episodes occurred.