COVID-19 patients also have high levels of production of anti-inflammatory cytokines, such as IL-10, perhaps as a way of compensating for the exacerbated inflammatory response, which can lead to a picture of immune dissonance and anergy towards the infection (26, 153–155). It is fundamental to perform further studies that elucidate the mechanisms of the immune response and the balance between pro-inflammatory and anti-inflammatory response patterns to understand the immunopathogenesis of COVID-19.