More recently, reports on COVID-19 have included the occurrence of coagulation abnormalities in most critically ill patients (128–131). Tang et al. (132) reported the occurrence of disseminated intravascular coagulation in 71.4% of non-surviving COVID-19 patients and in only 0.6% of surviving patients, suggesting a high frequency in severe COVID-19 patients. Autopsies performed on patients with COVID-19 also demonstrated small fibrinous thrombi in pulmonary arterioles with endothelial tumefaction, the presence of megakaryocytes, and indications of coagulation cascade activation (133).