Several studies found that CoVs can also affect other body regions, such as the gastrointestinal tract and ocular tissues (123, 124); some of them specifically investigated changes in the gastrointestinal tract and identified the presence of SARS-CoV-2 RNA in samples of anal/rectal swabs and feces of infected patients, establishing that the virus could be transmitted orally or fecally as well. Additionally, symptoms such as diarrhea, vomiting, and intestinal pain (125) have also been reported for SARS-CoV-2-positive patients, which can be associated with the expression of ACE2 in gastrointestinal epithelial cells, present especially in the small and large intestines, contributing to viral infection and replication in these cells (126).